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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8A1
All Species:
17.58
Human Site:
S617
Identified Species:
32.22
UniProt:
Q9Y2Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Q0
NP_006086.1
1164
131369
S617
A
V
A
E
I
S
E
S
D
F
Q
E
W
R
A
Chimpanzee
Pan troglodytes
XP_001150768
1164
131363
S617
A
V
A
E
I
S
E
S
D
F
Q
E
W
R
A
Rhesus Macaque
Macaca mulatta
XP_001099138
1164
131392
S617
A
V
A
E
I
S
E
S
D
F
Q
E
W
R
A
Dog
Lupus familis
XP_849357
1158
131123
Q614
E
I
S
E
S
D
F
Q
E
W
R
A
V
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70704
1149
129748
S602
A
V
A
E
I
S
E
S
D
F
E
E
W
R
A
Rat
Rattus norvegicus
XP_223390
1134
128100
I591
E
S
S
K
Y
K
E
I
T
L
K
H
L
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518853
932
104820
Y394
F
Q
E
W
R
V
V
Y
G
R
A
A
A
A
V
Chicken
Gallus gallus
XP_420729
1223
137907
S676
A
V
A
E
I
S
E
S
D
Y
Q
E
W
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666697
916
102033
N378
R
A
G
D
I
S
L
N
F
A
Y
N
L
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137649
1324
149578
D778
A
V
A
D
I
R
P
D
V
Y
Q
E
W
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200260
1167
132097
E604
A
F
R
E
I
S
K
E
E
Y
E
D
W
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XIE6
1213
137734
E640
A
Y
K
D
L
N
P
E
T
Y
D
S
W
N
E
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
G767
A
M
R
D
I
S
E
G
E
Y
E
E
W
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.8
96.9
N.A.
95.8
94.5
N.A.
74.4
88.5
N.A.
53.8
N.A.
50.9
N.A.
N.A.
57.6
Protein Similarity:
100
100
100
98
N.A.
97.7
96.3
N.A.
76.9
92.4
N.A.
63.4
N.A.
65.4
N.A.
N.A.
74.8
P-Site Identity:
100
100
100
6.6
N.A.
93.3
6.6
N.A.
0
80
N.A.
13.3
N.A.
46.6
N.A.
N.A.
40
P-Site Similarity:
100
100
100
40
N.A.
100
26.6
N.A.
0
86.6
N.A.
26.6
N.A.
60
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.2
39.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.6
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
8
47
0
0
0
0
0
0
8
8
16
8
8
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
31
0
8
0
8
39
0
8
8
0
0
8
% D
% Glu:
16
0
8
54
0
0
54
16
24
0
24
54
0
8
8
% E
% Phe:
8
8
0
0
0
0
8
0
8
31
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
70
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
8
8
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
8
0
0
8
0
0
16
16
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
0
8
0
16
0
% N
% Pro:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
0
39
0
0
0
24
% Q
% Arg:
8
0
16
0
8
8
0
0
0
8
8
0
0
31
0
% R
% Ser:
0
8
16
0
8
62
0
39
0
0
0
8
0
16
8
% S
% Thr:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
8
% T
% Val:
0
47
0
0
0
8
8
0
8
0
0
0
8
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
8
0
0
70
0
0
% W
% Tyr:
0
8
0
0
8
0
0
8
0
39
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _